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fredag 12 november 2010

Proteiinin laaduntarkkailu ja PDI entsyymi

Ihmisgeenit, jotka koodaavat proteiinidisulfidi-isomeraaseja

Wikipedia ja geenipankkilähteistä

Human genes encoding Protein disulfide isomerases include:

Chromosome + 16p13.3Chromosome 15 q15Chromosome + 7q35Chromosome + 3q21.1Chromosome + 2p25.1

Previous Symbols + TXNDC7
Previous Names + "thioredoxin domain containing 7 (protein disulfide isomerase)", "protein disulfide isomerase-associated 6"


From Wikipedia,
protein disulfide isomerase family A, member 3
Symbol PDIA3
Alt. symbols GRP58
Entrez 2923
HUGO 4606
OMIM 602046
RefSeq NM_005313
UniProt P30101
Other data
EC number
Locus Chr. 15 q15

Protein disulfide isomerase family A, member 3 (PDIA3) also known as glucose-regulated protein, 58-kD(GRP58) is an isomerase enzyme.[1][2][3]

The PDIA3 protein has protein disulfide isomerase activity.[3] PDIA3 is also part of the major histocompatibility complex (MHC) class I peptide-loading complex, which is essential for formation of the final antigen conformation and export from the endoplasmic reticulum to the cell surface.[4] See also

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