SULFATIDIN ja MUIDEN CEREBROSIDIJOHDANNAISTEN KATABOLIAN VIRHEITÄ
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982954/figure/Fig3/
Catabolism of complex SP and diseases associated with deficiencies in
these enzymes and/or activator proteins (Kolter and Sandhoff 2006). The color symbols and scheme for these compounds are the same as shown in Fig. 1 and and2.2.
The SP turnover-related diseases are indicated by number with:
(1)
GM1-gangliosidosis;
(2) Tay-Sachs disease/Sandhoff AB variant;
(3)
Sandhoff disease;
(4) Fabry disease;
(5) Sialidosis;
(6) Gaucher
disease;
(7) metachromatic leukodystrophy;
(8) globoid cell
leukodystrophy/Krabbe disease;
(9) Niemann Pick disease;
(10) Farber
disease. The abbreviations are as follows: Choline-P phosphatidylcholines; Et-P phosphatidylethanolamine; Glc glucose; GlcNAc N-acetylglucosamine; Gal galactose; GalNAc N-acetylgalactosamine; and NeuAc, N-acetylneuraminic acid
måndag 12 november 2012
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