Vitamiinit ja aivo

Neurosci Res. 1984;11(4):419-35.
Vitamin content of some normal human brain segments.

Baker H, Frank O, Chen T, Feingold S, DeAngelis B, Baker E.

Abstract

Nicotinates, pantothenates, riboflavin, vitamins B6 and B12' free (acetyl) and total (free and bound) choline, biopterin, thiamin, biotin, methylated and nonmethylated folates in frontal, temporal, precentral, postcentral, and occipital cortex, thalamus, cerebellum, pons, basal ganglia, and substantia nigra were estimated.

Nicotinates (B3-4 vitamin) are significantly more concentrated in basal ganglia and thalamus than pons.

Nonmethylated folate content is not significantly varied in brain segments;
the pons contains more methylated folate.

Riboflavin  (B2 vitamin)  content is higher in the basal ganglia and temporal cortex than frontal cortex.

Biotin is concentrated in pons and basal ganglia.

Thiamin (B1 vitamin) concentration is less in the postcentral cortex than the thalamus and substantia nigra.

Biopterin is significantly higher in substantia nigra and basal ganglia than the other brain segments.

Total choline content is high in substantia nigra, pons, and thalamus;
free (acetyl) choline is significantly elevated in basal ganglia.

B12 content is less concentrated in the cortex segments.

 B6 is highly concentrated in the basal ganglia.

Pantothenate  (B5 vitamin) content is elevated in pons when compared to the various cortex segments and cerebellum.

PMID:

6235380

DOI:

10.1002/jnr.490110409

[Indexed for MEDLINE]